First thing you need is an MPQ archiver.
http://www.gamefront.com/files/files/4684765/winmpq.zipRun winMPQ and open your HU patch_d2.mpq.
The archive is arranged alphabetically to make finding files a bit easier.
The .MPQ is simply a packed and compressed data folder.
For text files, look for files preceeded by data\global\excel\
For item image DC6's, look for files preceeded by data\global\items\
For string files, look for files preceeded by data\local\lng\eng\
Highlight the files you need then extract them to your desktop (or your HU folder if you like).
This will create a data folder with the files in the correct sub folders. (data\global\excel\ if it's text files you extracted etc.)
Runewords are all in runes.txt.
The runes used are listed by their rune number. (El is r01 for example).
Ps. You can use jewels and gems as runes in this file. Ie. jew, jew, jew would be a runeword from 3 jewels.
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